Accelerating compound identification in chemistry workflows
Chemistry is a broad field which comprises alot of fields with the same purpose: knowing what is inside the flask. The use of High-Resolution Mass Spectrometry techniques adds a valuable dimension to the standard low–resolution techniques, where the expected mass is the only value provided.
The high accuracy of the newest instruments provides enough reliability to use HRMS as identification tool, which can be enhanced if the instrument is equipped with the ion mobility technology, providing the collision cross section value, a fingerprinting value for compound identification.
Mass Analytica offers different software solutions focused onthe structural elucidation of your compound of interest.
The study of the compound degradation is mandatory for drug products and drug substances as it is stated in the FDA and ICH guidance state. These studies are done to understand their behavior over time under multiple environmental conditions. These properties are key to decide about the formulation, packaging, storage conditions and expiration date of the potential new drugs.
Most organic synthesis workflows end up with the synthesis of at least few milligrams of pure compound, which structure is corroborated by Nuclear Magnetic Resonance spectroscopy. Therefore, it needs first to use relatively large quantities of initial materials and purify the reaction crude before knowing if the desired compound has been obtained.