Imaging

Mass Spectrometry Imaging (MSI)

Mass Spectrometry Imaging (MSI) is an established and powerful MS technique that enables molecular mapping of tissues and cells finding widespread applications in academic, medical, and pharmaceutical industries. As both, applications and MSI technology, have undergone rapid growth and improvement, the challenges associated with analyzing large datasets and identifying the many detected molecular species have become apparent.

The lack of readily available and comprehensive software covering all necessary data analysis steps has further compounded this challenge- To address this issue, we developed LipostarMSI, comprehensive and vendor-neutral software for targeted and untargeted MSI data analysis.

Through user-friendly implementation of image visualization and co-registration, univariate and multivariate image and spectral analysis, and for the first time, advanced lipid, metabolite, and drug metabolite (MetID) automated identification, LipostarMSI effectively streamlines biochemical interpretation of the data. Here, we introduce LipostarMSI and case studies demonstrating the versatility and many capabilities of the software.

PUBLICATIONS

Articles:

Lipostar MSI: Comprehensive, Vendor-Neutral Software for Visualization, Data Analysis, and Automated Molecular Identification in Mass Spectrometry Imaging
- January 2020. Tortorella S, Tiberi P, Bowman AP, Claes BSR, Ščupáková K, Heeren RMA, Ellis SR, Cruciani G

Videos:

Ion Mobility MSI: Açdding A New Dimension To Spatial Metabolomics
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Jens Soltwisch

Spatial Localization And Identification Of Drug And Metabolites
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Giulia Coliva

Imaging

Imaging

Imaging

Mass Spectrometry Imaging (MSI)

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