LipostarMSI is a software for mass spectrometry imaging (MSI) that supports both untargeted and targeted data analysis, distributed as desktop application.
The workflow supported by LipostarMSI covers all the steps required for MSI data analysis: raw data processing, histological coregistration, manual drawing or importing of regions annotated by pathologists, image visualization, a variety of univariate and multivariate image and spectral analysis tools, co-localization analysis, and automated lipids, metabolites and drug metabolites annotation, including MS/MS-based identification.
A revolution in MSI for pharmaceutical and medical applications
- Both targeted and untargeted MSI data analysis supported, greatly streamlining biochemical interpretation of the data
- Customizable peak picking, pixel spectra alignment, data reduction
- Multiple images co-registration
- Automatic import of ROI annotated by expert pathologists using QuPath and Pannoramic Viewer
- Automatic metabolite and drug metabolite annotation
- Automatic MS/MS-based lipid identification
- Automatic report generation
- Tutorial 1 – Getting started with LipostarMSI
- Tutorial 2 – MSI file preview
- Tutorial 3 – First steps into LipostarMSI: from data import to ROI analysis and lipid identification
- Tutorial 4 – Multiple dataset analysis
- Tutorial 5 – Import annotations
- Tutorial 6 – The Lipostar DB manager and Lipid Builder
- Tutorial 7 – Background subtraction
- Tutorial 8 – Drug Metabolites Automatic Identification
Pharma – Data Analysis – Imaging
Articles:
- Lipostar MSI: Comprehensive, Vendor-Neutral Software for Visualization, Data Analysis, and Automated Molecular Identification in Mass Spectrometry Imaging
- January 2020. Tortorella S, Tiberi P, Bowman AP, Claes BSR, Ščupáková K, Heeren RMA, Ellis SR, Cruciani G
Videos:
- Ion Mobility MSI: Açdding A New Dimension To Spatial Metabolomics
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Jens Soltwisch
- Spatial Localization And Identification Of Drug And Metabolites
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Giulia Coliva
Life Sciences – Imaging Metabolites
Articles:
- Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers
- January 2021. Shane R. Ellis, Emily Hall, Madhuriben Panchal, Bryn Flinders, Jens Madsen, Grielof Koster, Ron.M.A. Heeren, Howard W. Clark, Anthony D. Postle
- Comprehensive, Vendor-Neutral Software for Visualization, Data Analysis, and Automated Molecular Identification in Mass Spectrometry Imaging
- January 2020. Tortorella S, Tiberi P, Bowman AP, Claes BSR, Ščupáková K, Heeren RMA, Ellis SR, Cruciani G.
Videos:
- Comprehensive, Vendor-Neutral, High-Throughput Imaging Mass Spectrometry Data Analysis
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella
- Ion Mobility MSI: Adding A New Dimension To Spatial Metabolomics
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Jens Soltwisch
- Spatial Localization And Identification Of Drug And Metabolites
- Practical Applications for Drug Discovery 2020 Webinar. Sara Tortorella, Giulia Coliva
- Lipostar: Software dedicated to LC-MS lipidomics as a desktop application
- Mars: Software dedicated to LC-MS metabolomics as a desktop application
- Action: Software dedicated to affinity measurement as a desktop application
